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Proteintech
PRDM4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
13792-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRDM4 Fusion Protein Ag4580 (451-801 aa encoded by BC035581)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EVAEWTDKA VNHIWKIYHN GVLEFCIITT DENECNWMMF VRKARNREEQ NLVAYPHDGK IFFCTSQDIP PENELLFYYS RDYAQQIGVP EHPDVHLCNC GKECNSYTEF KAHLTSHIHN HLPTQGHSGS HGPSHSKERK WKCSMCPQAF ISPSKLHVHF MGHMGMKPHK CDFCSKAFSD PSNLRTHLKI HTGQKNYRCT LCDKSFTQKA HLESHMVIHT GEKNLKCDYC DKLFMRRQDL KQHVLIHTQE RQIKCPKCDK LFLRTNHLKK HLNSHEGKRD YVCEKCTKAY LTKYHLTRHL KTCKGPTSSS SAPEEEEEDD SEEEDLADSV GTEDCRINSA VYSADESLSA HK (451-801 aa encoded by BC035581)
靶标信息
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC45046; PR domain 4; PR domain containing 4; PR domain-containing protein 4; PR-domain zinc-finger protein PFM1; unnamed protein product
基因别名: 1700031E19Rik; 2810470D21Rik; PFM1; SC-1; SC1
UniProt ID: (Human) Q9UKN5, (Rat) Q9QZP2, (Mouse) Q80V63
Entrez Gene ID: (Human) 11108, (Rat) 170820, (Mouse) 72843
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
histone methyltransferase binding
sequence-specific double-stranded DNA binding
death receptor binding
transcription from RNA polymerase II promoter
regulation of gene expression
negative regulation of gene expression
negative regulation of cell growth
cellular response to nutrient
positive regulation of transcription from RNA polymerase II promoter
cellular response to growth factor stimulus
regulation of neural precursor cell proliferation
regulation of stem cell differentiation
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