Proteintech

PRDM8 Polyclonal Antibody

查看其他2个PRDM8抗体

问题与答案

问题与答案

问题与答案

抗体检测数据 (3)

PRDM8 Antibody in Western Blot (WB)

PRDM8 Antibody in Western Blot (WB)

图: 1 / 3

PRDM8 Antibody (26010-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 26010-1-AP (PRDM8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

PRDM8 Antibody in Western Blot (WB)

PRDM8 Antibody in Western Blot (WB)

PRDM8 Antibody in Western Blot (WB)

Product Image Gallery

PRDM8 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 26010-1-AP (PRDM8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

PRDM8 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 26010-1-AP (PRDM8 antibody) at dilution of 1:1,000 incubated at room temperature for 1.5 hours.

PRDM8 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 26010-1-AP (PRDM8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Immunogen image

PRDM8 Polyclonal Antibody

Immunogen Image PRDM8 Polyclonal Antibody

产品信息

26010-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

酶联免疫吸附实验 (ELISA)

Assay-dependent

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

PRDM8 fusion protein Ag23373

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.45 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Immunogen sequence: MEDTGIQRGI WDGDAKAVQQ CLTDIFTSVY TTCDIPENAI FGPCVLSHTS LYDSIAFIAL KSTDKRTVPY IFRVDTSAAN GSSEGLMWLR LVQSARDKEE QNLEAYIKNG QLFYRSLRRI AKDEELLVWY GKELTELLLL CPSRSHNKMN GSSPYTCLEC SQRFQFEFPY VAHLRFRCPK RLHSADISPQ DEQGGGVGTK DHGGGGGGGK DQQQQQQEAP LGPGPKFCKA GPLHHYPSPS PESSNPSAAA GGSSAKPSTD FHNLARELEN SRGGSSCSPA QSLSSGSGSG GGGGHQEAEL SPDGIATGGG KGKRKFPEEA AEGGGGAGLV GGRGRFVERP LPASKEDLVC

靶标信息

Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: PR domain zinc finger protein 8; PR domain-containing protein 8; PR-domain containing protein 8

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基因别名: 4930565F05Rik; EPM10; PFM5; PRDM8

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UniProt ID: (Human) Q9NQV8, (Mouse) Q8BZ97

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Entrez Gene ID: (Human) 56978, (Mouse) 77630, (Rat) 305198

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DNA binding protein binding methyltransferase activity metal ion binding rRNA (adenine-N6,N6-)-dimethyltransferase activity chromatin binding transcription corepressor activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity histone methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity histone methyltransferase activity (H3-K9 specific) P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity molecular_function

transcription, DNA-templated regulation of transcription, DNA-templated histone methylation corpus callosum morphogenesis central nervous system projection neuron axonogenesis corticospinal tract morphogenesis neurogenesis methylation negative regulation of transcription, DNA-templated histone H3-K9 methylation biological_process peptidyl-lysine methylation oligodendrocyte development