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Proteintech
PREP Polyclonal Antibody
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产品信息
11536-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PREP Fusion Protein Ag2101 (360-710 aa encoded by BC030636)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ILQLHDLTT GALLKTFPLD VGSIVGYSGQ KKDTEIFYQF TSFLSPGIIY HCDLTKEELE PRVFREVTVK GIDASDYQTV QIFYPSKDGT KIPMFIVHKK GIKLDGSHPA FLYGYGGFNI SITPNYSVSR LIFVRHMGGI LAVANIRGGG EYGETWHKGG ILANKQNCFD DFQCAAEYLI KEGYTSPKRL TINGGSNGGL LVAACANQRP DLFGCVIAQV GVMDMLKFHK YTIGHAWTTD YGCSDSKQHF EWLVKYSPLH NVKLPEADDI QYPSMLLLTA DHDDRVVPLH SLKFIATLQY IVGRSRKQSN PLLIHVDTKA GHGAGKPTAK VIEEVSDMFA FIARCLNVDW IP (360-710 aa encoded by BC030636)
靶标信息
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250|UniProtKB:P23687}; Post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250|UniProtKB:P23687}; prep {ECO:0000312|RGD:620841}; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250|UniProtKB:P23687}; prolyl oligopeptidase; rPop
基因别名: AI047692; AI450383; D10Wsu136e; PE; PEP; Pop; PREP; rPop
UniProt ID: (Human) P48147, (Mouse) Q9QUR6, (Rat) O70196
Entrez Gene ID: (Human) 5550, (Mouse) 19072, (Rat) 83471
