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Fabgennix
PREX1 Polyclonal Antibody, Biotin
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产品信息
PREX-BIOTIN
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.Sequence:QEEDQADSAFPLLSLGPRLSLC
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000031228; P-Rex1; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; PIP3 dependent Rac exchange factor 1; PREX 1; PREX-1; ptdIns(3,4,5)-dependent Rac exchanger 1; SET domain containing 6
基因别名: G630042G04; KIAA1415; P-REX1; PREX1; RGD1306534; Setd6
UniProt ID: (Human) Q8TCU6, (Mouse) Q69ZK0
Entrez Gene ID: (Human) 57580, (Mouse) 277360, (Rat) 311647
superoxide metabolic process
G-protein coupled receptor signaling pathway
actin filament polymerization
T cell differentiation
neutrophil chemotaxis
regulation of actin filament polymerization
regulation of Rho protein signal transduction
intracellular signal transduction
neutrophil activation
positive regulation of GTPase activity
regulation of dendrite development
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of cell adhesion
reactive oxygen species metabolic process
