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Recommended positive controls: HeLa.
Predicted reactivity: Mouse (88%), Rat (90%), Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Caveolae-associated protein 3; Cavin-3; hSRBC; MGC20400; Protein kinase C delta-binding protein; protein kinase C, delta binding protein; sdr-related gene product that binds to c-kinase; Serum deprivation response factor-related gene product that binds to C-kinase
基因别名: cavin-3; CAVIN3; HSRBC; PRKCDBP; SRBC
UniProt ID: (Human) Q969G5
Entrez Gene ID: (Human) 112464