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Proteintech
PRKD2 Polyclonal Antibody
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产品信息
11623-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRKD2 Fusion Protein Ag2192 (189-538 aa encoded by BC025307)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SLSISVSNS QIQENVDIAT VYQIFPDEVL GSGQFGVVYG GKHRKTGRDV AVKVIDKLRF PTKQESQLRN EVAILQSLRH PGIVNLECMF ETPEKVFVVM EKLHGDMLEM ILSSEKGRLP ERLTKFLITQ ILVALRHLHF KNIVHCDLKP ENVLLASADP FPQVKLCDFG FARIIGEKSF RRSVVGTPAY LAPEVLLNQG YNRSLDMWSV GVIMYVSLSG TFPFNEDEDI NDQIQNAAFM YPASPWSHIS AGAIDLINNL LQVKMRKRYS VDKSLSHPWL QEYQTWLDLR ELEGKMGERY ITHESDDARW EQFAAEHPLP GSGLPTDRDL GGACPPQDHD MQGLAERISV L (189-538 aa encoded by BC025307)
靶标信息
PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: nPKC-D2; Serine/threonine-protein kinase D2
基因别名: AI325941; HSPC187; nPKC-D2; PKD2; PRKD2; RGD1308054
UniProt ID: (Human) Q9BZL6, (Rat) Q5XIS9, (Mouse) Q8BZ03
Entrez Gene ID: (Human) 25865, (Rat) 292658, (Mouse) 101540
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
metal ion binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
angiogenesis
positive regulation of endothelial cell proliferation
adaptive immune response
protein phosphorylation
cell adhesion
cell death
positive regulation of endothelial cell migration
peptidyl-serine phosphorylation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-2 production
positive regulation of interleukin-8 production
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of blood vessel endothelial cell migration
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
endothelial tube morphogenesis
positive regulation of ERK1 and ERK2 cascade
protein kinase D signaling
mitophagy in response to mitochondrial depolarization
positive regulation of histone deacetylase activity
positive regulation of intracellular signal transduction
positive regulation of DNA biosynthetic process
positive regulation of endothelial cell chemotaxis
immune system process
phosphorylation
