应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:200-1:2,000 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 409-608 of human CARM1. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.56 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2807902 |
Immunogen sequence: TEPLTHWYQV RCLFQSPLFA KAGDTLSGTC LLIANKRQSY DISIVAQVDQ TGSKSSNLLD LKNPFFRYTG TTPSPPPGSH YTSPSENMWN TGSTYNLSSG MAVAGMPTAY DLSSVIASGS SVGHNNLIPL ANTGIVNHTH SRMGSIMSTG IVQGSSGAQG SGGGSTSAHY AVNSQFTMGG PAISMASPMS IPTNTMHYGS; Positive Samples: 22Rv1, A-431, Mouse spleen, Rat brain; Cellular Location: Cytoplasm, Nucleus
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; Histone-arginine methyltransferase CARM1; protein arginine methyltransferase; Protein arginine N-methyltransferase 4
基因别名: CARM1; PRMT4
UniProt ID: (Human) Q86X55, (Mouse) Q9WVG6, (Rat) Q4AE70
Entrez Gene ID: (Human) 10498, (Mouse) 59035, (Rat) 363026
分子生物学功能:
protein modifying enzyme