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Invitrogen
PRMT8 Polyclonal Antibody
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PRMT8 Antibody (PA5-143984) in IHC (P)
Immunohistochemistry analysis of PRMT8 in paraffin-embedded section of rat brain tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with PRMT8 Polyclonal antibody (Product # PA5-143984) using a dilution of 1 μg/mL overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as s... View More
产品信息
PA5-143984
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human PRMT8 recombinant protein (Position: M3-E171).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, human U-87MG whole cell. IHC: human meningeoma tissue, human meningeoma tissue, rat brain tissue, rat brain tissue. Flow: THP-1 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: arginine methyltransferase 8; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; Protein arginine N-methyltransferase 8
基因别名: HRMT1L3; HRMT1L4; PRMT8
UniProt ID: (Human) Q9NR22
Entrez Gene ID: (Human) 56341, (Rat) 688502
protein binding
histone-arginine N-methyltransferase activity
S-adenosylmethionine-dependent methyltransferase activity
protein-arginine omega-N monomethyltransferase activity
protein-arginine omega-N asymmetric methyltransferase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
molecular_function
histone methyltransferase activity (H4-R3 specific)
protein modifying enzyme
