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Proteintech
PROS1 Polyclonal Antibody, CoraLite® Plus 488
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PROS1 Antibody (CL488-16910) in Flow
1x10^6 HepG2 cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human PROS1 (CL488-16910) (red), or 0.4 µg CoraLite® Plus 488-conjugated Rabbit IgG control Rabbit PolyAb (CL488-30000) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
产品信息
CL488-16910
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PROS1 fusion protein Ag10539
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: DFRTYDSEG VILYAESIDH SAWLLIALRG GKIEVQLKNE HTSKITTGGD VINNGLWNMV SVEELEHSIS IKIAKEAVMD INKPGPLFKP ENGLLETKVY FAGFPRKVES ELIKPINPRL DGCIRSWNLM KQGASGIKEI IQEKQNKHCL VTVEKGSYYP GSGIAQFHID YNNVSSAEGW HVNVTLNIRP STGTGVMLAL VSGNNTVPFA VSLVDSTSEK SQDILLSVEN TVIYRIQALS LCSDQQSHLE FRVNRNNLEL STPLKIETIS HEDLQRQLAV LDKAMKAKVA TYLGGLPDVP FSATPVNAFY NGCMEVNING VQLDLDEAIS KHNDIRAHSC PSVWKKTKNS
靶标信息
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
基因别名: AW214361; PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) P07225, (Mouse) Q08761
Entrez Gene ID: (Human) 5627, (Mouse) 19128
platelet degranulation
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
negative regulation of endopeptidase activity
peptidyl-glutamic acid carboxylation
regulation of complement activation
response to lipopolysaccharide
fibrinolysis
positive regulation of phagocytosis
leukocyte migration
hemostasis
negative regulation of coagulation
