Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
PROTEIN S Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
PROTEIN S Antibody (PA5-90849) in WB
Western blot analysis of PROTEIN S in extracts of various cell lines. Samples were incubated with PROTEIN S Polyclonal antibody (Product # PA5-90849) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-90849
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_0003042)
偶联物
形式
Liquid
浓度
2.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MDINKPGPLF KPENGLLETK VYFAGFPRKV ESELIKPINP RLDGCIRSWN LMKQGASGIK EIIQEKQNKH CLVTVEKGSY YPGSGIAQFH IDYNNVSSAE GWHVNVTLNI RPSTGTGVML ALVSGNNTVP FAVSLVDSTS EKSQDILLSV ENTVIYRIQA LSLCSDQQSH LEFRVNRNNL ELSTPLKIET ISHEDLQRQL AVLDKAMKAK VATYLGGLPD VPFSATPVNA FYNGCMEVNI NGVQLDLDEA ISKHNDIRAH SCPSVWKKTK NS; Positive Samples: LO2, HeLa, 293T, Mouse liver, Mouse kidney, Rat liver, Rat kidney
靶标信息
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
基因别名: AW214361; PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) P07225, (Mouse) Q08761
Entrez Gene ID: (Human) 5627, (Rat) 81750, (Mouse) 19128
platelet degranulation
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
negative regulation of endopeptidase activity
peptidyl-glutamic acid carboxylation
regulation of complement activation
response to lipopolysaccharide
fibrinolysis
positive regulation of phagocytosis
leukocyte migration
negative regulation of coagulation
hemostasis
