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Agrisera
PRP40B/pre-mRNA-processing protein 40B Polyclonal Antibody
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PRP40B/pre-mRNA-processing protein 40B Antibody (AS14-2785) in WB
Total protein from rosette leaves, 30 µg of Arabidopsis thaliana whole leaf extract (prp 40 ab) (1), 30 µg of Arabidopsis thaliana whole leaf extract (wild-type) (2), extracted with buffer (100 m M Tris, 10% glycerol, 5 m M EDTA, 5 m M EGTA, 0.15 M Na Cl, 0.75% Triton X 100,0.05% SDS, 1 m M DTT) and denatured with 0.06 M Tris-HCl, 5% glycerol, 2% SDS, 4% β-mercaptoethanol, 0.25% bromophenol blue at 95 C for... View More
产品信息
AS14-2785
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant Arabidopsis thaliana PRP40b.
偶联物
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
PRPF40B encodes an intracellular, predominantly nuclear protein that localizes to nucleoplasm/nuclear bodies (with additional cytosolic signal) and is structurally characterized by N-terminal WW protein-interaction module(s) together with multiple FF domains, consistent with an adaptor/scaffold architecture in RNA-processing pathways. Alternative splicing generates multiple transcript variants encoding distinct isoforms. Based on homology to the yeast U1 snRNP factor Prp40 and curated functional annotations, PRPF40B is implicated in pre-mRNA processing and mRNA splicing, likely contributing to early spliceosome/U1 snRNP-associated protein-protein interactions via its WW and FF domains. Reported interaction data indicate PRPF40B can bind Huntingtin and MeCP2, supporting a role as a multi-partner interaction hub that may link spliceosomal functions with other nuclear protein networks.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: At5g03340; AtPRP40B; HYPC
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