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Invitrogen
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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human Pancreasin/Marapsin/PRSS27.
PRSS27, also known as Marapsin, is a gene located on chromosome 16p13.3 that encodes a serine protease enzyme. This protein is part of the trypsin-like serine protease family, which is characterized by a catalytic triad essential for proteolytic activity. PRSS27 is primarily expressed in the epidermis and other epithelial tissues, such as the salivary glands and pancreas. It plays a role in various physiological processes, including digestion, inflammation, and immune response regulation. In the skin, PRSS27 is involved in keratinocyte differentiation and the maintenance of skin barrier function. Dysregulation or altered expression of PRSS27 has been associated with inflammatory skin conditions, such as psoriasis, where it may influence the inflammatory cascade and contribute to disease pathogenesis. Research into PRSS27 continues to explore its potential role in epithelial homeostasis and as a therapeutic target for skin-related and other inflammatory disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAP-2; channel-activating protease 2; EC 3.4.21; EC 3.4.21.4; EC 3.4.21.43; Marapsin; MPNMarapsin; Pancreasin; Serine protease 27
基因别名: CAPH2; MPN; PRSS27; UNQ1884/PRO4327
UniProt ID: (Human) Q9BQR3
Entrez Gene ID: (Human) 83886