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Invitrogen
PRX Polyclonal Antibody
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PRX Antibody (PA5-79887) in WB
Western blot analysis of PRX in Lane 1: rat kidney tissue lysate, Lane 2: mouse kidney tissue lysate, Lane 3: human 293T whole cell lysate, Lane 4: human HK-2 whole cell lysate using 50 µg (reducing conditions) per well. Electrophoresis was performed on 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours and protein was transferred to a nitrocellulose membrane at 150mA for 50-90 minutes. Sample was blocked with 5% Non-fat Milk/TBS for 1.5 hours at room temperature, incubated with PRX polyclonal antibody (Product # ... View More
产品信息
PA5-79887
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human PRX recombinant protein (Position: M1-K91).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Jurkat whole cell, human K562 whole cell, humna U2OS whole cell, human U251 whole cell, rat brain tissue, mouse brain tissue. Flow: K562 cell.
靶标信息
Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Periaxin
基因别名: CMT4F; KIAA1620; L-Periaxin; PRX
UniProt ID: (Human) Q9BXM0, (Mouse) O55103, (Rat) Q63425
Entrez Gene ID: (Human) 57716, (Mouse) 19153, (Rat) 78960
