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Proteintech
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Immunogen sequence: MYALFLLAS LLGAALAGPV LGLKECTRGS AVWCQNVKTA SDCGAVKHCL QTVWNKPTVK SLPCDICKDV VTAAGDMLKD NATEEEILVY LEKTCDWLPK PNMSASCKEI VDSYLPVILD IIKGEMSRPG EVCSALNLCE SLQKHLAELN HQKQLESNKI PELDMTEVVA PFMANIPLLL YPQDGPRSKP QPKDNGDVCQ DCIQMVTDIQ TAVRTNSTFV QALVEHVKEE CDRLGPGMAD ICKNYISQYS EIAIQMMMHM QPKEICALVG FCDEVKEMPM QTLVPAKVAS KNVIPALELV EPIKKHEVPA KSDVYCEVCE F
PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Proactivator polypeptide; Prosaposin; sphingolipid activator protein-1
基因别名: GLBA; PSAP; SAP1
UniProt ID: (Human) P07602
Entrez Gene ID: (Human) 5660