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Invitrogen
PSCA Polyclonal Antibody
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产品信息
PA1-20936
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the extracellular region of the human protein.
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-20936 detects PSCA in Human samples.
PA1-20936 has been successfully used in Immunohistochemistry (Paraffin) procedures. Staining of formalin fixed tissues requires boiling tissue section in 10 mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at room temperature for 20 minutes. Suggested positive controls for this product are bladder and prostate carcinomas.
PA1-20936 immunogen corresponds to Synthetic peptide corresponding to the extracellular region of the human protein.
靶标信息
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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