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Invitrogen
PSCA Polyclonal Antibody
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PSCA Antibody (PA5-32566) in IHC
Immunohistochemical analysis of Prostate Stem Cell Antigen using anti-Prostate Stem Cell Antigen Polyclonal Antibody (Product # PA5-32566) in Prostate Adenocarcinoma Cancer Tissue. The recommened dilution for this antibody in immunohistochemistry applications is 1:75.
产品信息
PA5-32566
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from extracellular region of human PSCA protein.
偶联物
形式
Liquid
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is breast, bladder or prostate adenocarcinoma.
靶标信息
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
