应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:1,000-1:2,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:150 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
流式细胞分析 (Flow) |
1:100 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Mouse / IgG2b |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
OTI1C4 |
抗原 |
Human recombinant protein fragment corresponding to amino acids 21-219 of PSMB9 produced in HEK293T cell |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.65 mg/mL |
纯化类型 |
Affinity Chromatography |
保存液 |
PBS, pH 7.3, with 1% BSA, 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2725132 |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: large multifunctional peptidase 2; large multifunctional protease 2; LMP-2d; Low molecular mass protein 2; Macropain chain 7; MGC70470; Multicatalytic endopeptidase complex chain 7; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); proteasome catalytic subunit 1i; Proteasome chain 7; proteasome subunit beta 6i; proteasome subunit beta type 9; Proteasome subunit beta type-9; Proteasome subunit beta-1i; proteasome-related gene 2; proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2); proteosome beta 9 subunit; Really interesting new gene 12 protein
基因别名: beta1i; Lmp-2; LMP2; PSMB6i; PSMB9; RING12
UniProt ID: (Human) P28065, (Mouse) P28076
Entrez Gene ID: (Human) 5698, (Mouse) 16912
分子生物学功能:
protease