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Invitrogen
PSMD11 Polyclonal Antibody
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PSMD11 Antibody (PA5-27447) in ICC/IF
Immunofluorescent analysis of PSMD11 showing staining in the nucleus and cytoplasm of A549 cells. A549 cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a PSMD11 polyclonal antibody (Product # PA5-27447) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-27447
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 266 and 422 of Human PSMD11
偶联物
形式
Liquid
浓度
0.68 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA5-27447 targets PSMD11 in WB applications and shows reactivity with Human samples.
The PA5-27447 immunogen is recombinant fragment corresponding to a region within amino acids 266 and 422 of Human PSMD11.
靶标信息
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
