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Immunogen sequence: MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE DKMDGAPSRV LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH LRNQPIYIQY SNHKELKTDN TLNQRAQAVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG; Positive Samples: SH-SY5Y, HeLa, Mouse brain, Mouse testis, Rat testis; Cellular Location: Nucleus
PTBP2 encodes a protein that binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.
Protein Aliases: br n nPTB5; Brain-enriched polypyrimidine tract-binding protein; Brain-enriched PTB; neural polypyrimidine tract binding protein; Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; nPTB5; nPTB6; nPTB7; nPTB8; Polypyrimidine tract-binding protein 2; PTB-like protein; RRM-type RNA-binding protein brPTB
Gene Aliases: Brptb; NPTB; PTB; Ptb2; PTBLP; PTBP2