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产品信息
PA1-32793
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 19 amino acid peptide from 3 rd cytoplasmic domain of human PTGDR
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2174481
产品详细信息
PA1-32793 detects PTGDR from human samples.
靶标信息
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
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生物信息学
蛋白别名: Dp receptor; MGC49004; PGD receptor; PGD2 receptor; Prostaglandin D2 receptor; prostaglandin D2 receptor (DP); Prostanoid DP receptor
基因别名: AS1; ASRT1; DP; DP1; PTGDR; PTGDR1
UniProt ID: (Human) Q13258
Entrez Gene ID: (Human) 5729
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
male sex determination
sleep
positive regulation of vasodilation
adenosine metabolic process
cellular response to prostaglandin D stimulus
