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Invitrogen
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PA1-20764 detects Prostaglandin E Receptor EP4 in Human samples.
PA1-20764 has been successfully used in Immunocytochemistry and Immunohistochemistry (Paraffin) procedures.
PA1-20764 immunogen corresponds to Synthetic peptide conjugated to KLH (aa sequence is considered to be commercially sensitive)..
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2. This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1, regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。