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Invitrogen
PTH1R Polyclonal Antibody
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PTH1R Antibody (PA5-32538) in IHC
Immunohistochemical analysis of Parathyroid Hormone Receptor 1 using anti-Parathyroid Hormone Receptor 1 Polyclonal Antibody (Product # PA5-32538) in Parathyroid Cancer Tissue. The recommened dilution for this antibody in immunohistochemistry applications is 1:50.
产品信息
PA5-32538
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to N-terminus of human parathyroid hormone receptor type 1.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is parathyroid tissue.
靶标信息
Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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