Invitrogen

PTHLH Polyclonal Antibody

2个已发表图片

3 篇参考文献

查看其他10个PTHLH抗体

抗体检测数据 (4)
已发表图片 (2)

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PTHLH Antibody (PA5-40799) in IHC (P)

Immunohistochemistry (paraffin-embedded) analysis of human kidney tissue using an anti-PTHLH polyclonal antibody (Product # PA5-40799).

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PTHLH Antibody in Western Blot (WB)

PTHLH Antibody in Western Blot (WB)

PTHLH Antibody in Western Blot (WB)

PTHLH Antibody in Western Blot (WB)

Product Image Gallery

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human kidney tissue using an anti-PTHLH polyclonal antibody (Product # PA5-40799).

PTHLH Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human lung tissue using an anti-PTHLH polyclonal antibody (Product # PA5-40799).

PTHLH Antibody in Western Blot (WB) — Western blot analysis of human HepG2 cell lysate using an anti-PTHLH polyclonal antibody (Product # PA5-40799).

PTHLH Antibody in Western Blot (WB) — Western blot analysis of human, mouse, rat cells using an anti-PTHLH polyclonal antibody (Product # PA5-40799).

PTHLH Antibody in Western Blot (WB) — Figure 3. Changes in the signaling pathways of Ihh, PTrP, and Wnt in ATDC5 cells with the addition of statin. (A) Ihh. (B) PTHrP. (C) Smo. (D) Ptch1. ITS (insulin, transferrin, sodium selenite) was added on day 0 and was normalized according to the control value of day 7. For the significant difference test, the Tukey-Kramer test was conducted. (E) Comparison of protein amounts of Ihh and PTHrP by Western blot on days 7, 14, and 21 after induction of differentiation with 1% ITS. (F) Comparison of protein amounts related to Ihh pathway and Wnt pathway by western blot on day 21 after induction of differentiation with 1% ITS. The graph values denote the average +- SD ( n = 3), * P < 0.05 and ** P < 0.01, estimated by analysis of variance followed by post hoc Tukey-Kramer and compared with control group at same time point.

PTHLH Antibody in Western Blot (WB) — Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

产品信息

PA5-40799

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化（石蜡） (IHC (P))

4-8 µg/mL

-

免疫组织化学（多聚甲醛固定） (IHC (PFA))

-

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产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human PTHLH

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2609473

产品详细信息

Peptide sequence: YKEQPLKTPG KKKKGKPGKR KEQEKKKRRT RSAWLDSGVT GSGLEGDHLS

Sequence homology: Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

靶标信息

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification.

Cartilage

Ishikawa M,Ishii T,Morikawa T,Iijima Y,Sueishi K

Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

Wed Dec 01 00:00:00 EST 2021

The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification.

Cartilage

Ishikawa M,Ishii T,Morikawa T,Iijima Y,Sueishi K

Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

Wed Dec 01 00:00:00 EST 2021

The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification.

Cartilage

Ishikawa M,Ishii T,Morikawa T,Iijima Y,Sueishi K

Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

Wed Dec 01 00:00:00 EST 2021

Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.

Molecular & cellular proteomics : MCP

van Herwijnen MJ,Zonneveld MI,Goerdayal S,Nolte-'t Hoen EN,Garssen J,Stahl B,Maarten Altelaar AF,Redegeld FA,Wauben MH

Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

Tue Nov 01 00:00:00 EDT 2016

Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.

Molecular & cellular proteomics : MCP

van Herwijnen MJ,Zonneveld MI,Goerdayal S,Nolte-'t Hoen EN,Garssen J,Stahl B,Maarten Altelaar AF,Redegeld FA,Wauben MH

Published figure using PTHLH polyclonal antibody (Product # PA5-40799) in Western Blot

Tue Nov 01 00:00:00 EDT 2016

生物信息学

蛋白别名: osteostatin; parathyroid hormone related peptide; parathyroid hormone-like hormone preproprotein; Parathyroid hormone-like protein; parathyroid hormone-like related protein; Parathyroid hormone-related protein; PLP; PTH-related protein; PTH-rP

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基因别名: BDE2; HHM; PLP; PTHLH; PTHR; PTHRP

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UniProt ID: (Human) P12272

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Entrez Gene ID: (Human) 5744

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hormone activity peptide hormone receptor binding peptide hormone

参与通路

skeletal system development osteoblast development adenylate cyclase-activating G-protein coupled receptor signaling pathway cell-cell signaling female pregnancy positive regulation of cell proliferation negative regulation of cell proliferation epidermis development regulation of gene expression positive regulation of cAMP biosynthetic process negative regulation of chondrocyte differentiation cAMP metabolic process