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Proteintech
PTTG1IP Polyclonal Antibody
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产品信息
12575-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PTTG1IP Fusion Protein Ag3250 (1-180 aa encoded by BC012858)
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAPGVARGP TPYWRLRLGG AALLLLLIPV AAAQEPPGAA CSQNTNKTCE ECLKNVSCLW CNTNKACLDY PVTSVLPPAS LCKLSSARWG VCWVNFEALI ITMSVVGGTL LLGIAICCCC CCRRKRSRKP DRSEEKAMRE REERRIRQEE RRAEMKTRHD EIRKKYGLFK EENPYARFEN N (1-180 aa encoded by BC012858)
靶标信息
This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: PBF; Pituitary tumor-transforming gene 1 protein-interacting protein; Pituitary tumor-transforming gene protein-binding factor; PTTG-binding factor
基因别名: C21orf1; C21orf3; PBF; PTTG1IP
UniProt ID: (Human) P53801
Entrez Gene ID: (Human) 754
protein import into nucleus
positive regulation of protein ubiquitination
negative regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of cellular protein catabolic process
