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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:5,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:20-1:200 | - |
免疫细胞化学 (ICC/IF) |
1:50-1:200 | - |
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human Pentraxin-related protein PTX3 protein (99-164AA) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
3.555 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.03% Proclin 300 |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2812716 |
Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of "long pentraxins", which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: long pentraxin 3; Pentaxin-related protein PTX3; pentraxin related; Pentraxin-related protein PTX3; TNF alpha-induced protein 5; TSG-14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14
基因别名: PTX3; TNFAIP5; TSG-14; TSG14
UniProt ID: (Human) P26022
Entrez Gene ID: (Human) 5806, (Rat) 689388
