Proteintech

PYGL Monoclonal Antibody (1G12D8)

Name: PYGL Monoclonal Antibody (1G12D8)
Brand: Proteintech
SKU: 66769-1-IG

查看其他14个PYGL抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

图: 1 / 2

PYGL Antibody (66769-1-IG) in WB

HSC-T6 cells were subjected to SDS PAGE followed by western blot with 66769-1-IG (PYGL antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image PYGL Monoclonal Antibody (1G12D8)

产品信息

66769-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

1G12D8

抗原

PYGL Fusion Protein Ag8550 (499-846 aa encoded by BC009895)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: GLAELIAEK IGEDYVKDLS QLTKLHSFLG DDVFLRELAK VKQENKLKFS QFLETEYKVK INPSSMFDVQ VKRIHEYKRQ LLNCLHVITM YNRIKKDPKK LFVPRTVIIG GKAAPGYHMA KMIIKLITSV ADVVNNDPMV GSKLKVIFLE NYRVSLAEKV IPATDLSEQI STAGTEASGT GNMKFLNGAL TIGTMDGANV EMAEEAGEEN LFIFGMRIDD VAALDKKGYE AKEYYEALPE LKLVIDQIDN GFFSPKQPDL FKDIINMLFY HDRFKVFADY EAYVKCQDKV SQLYMNPKAW NTMVLKNIAA SGKFSSDRTI KEYAQNIWNV EPSDLKISLS NESNKVNGN (499-846 aa encoded by BC009895)

靶标信息

This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。