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Invitrogen
PYY Polyclonal Antibody
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产品信息
PA1-36142
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic porcine Peptide YY.
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存条件
4°C
运输条件
Wet ice
RRID
产品详细信息
A suggested positive control for IHC is rat colon tissue. An overnight incubation at 4°C is recommended.
Reconstitute with 50-100 µL of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide.
靶标信息
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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