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Invitrogen
PZP Polyclonal Antibody
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PZP Antibody (PA5-110249) in WB
Western blot analysis of PZP in extracts of various cell lines. Samples were incubated with PZP Polyclonal antibody (Product # PA5-110249) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110249
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2).
偶联物
形式
Liquid
浓度
0.92 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VKDLTNFPDN VDQQEEEQGH CPRPFFIHNG AIYVPLSSNE ADIYSFLKGM GLKVFTNSKI RKPKSCSVIP SVSAGAVGQG YYGAGLGVVE RPYVPQLGTY NVIPLNNEQS SGPVPETVRS Y
靶标信息
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: A1m {ECO:0000312|EMBL:AAA40723.1}; alpha 1 macroglobulin; Alpha-1-M; Alpha-1-macroglobulin; Alpha-1-macroglobulin 165 kDa subunit; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; Pregnancy zone protein; pregnancy-zone protein
基因别名: A1m; A2m; AI893533; CPAMD6; MAM; Pzp
UniProt ID: (Rat) Q63041
Entrez Gene ID: (Human) 5858, (Mouse) 11287, (Rat) 252922
