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Invitrogen
Phospho-Acinus (Ser1180) Polyclonal Antibody
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Phospho-Acinus (Ser1180) Antibody (PA5-105962) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-Acinus (Ser1180) in human gastric cancer tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-Acinus (Ser1180) polyclonal antibody (Product # PA5-105962) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105962
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ACIN1(Accession Q9UKV3), corresponding to amino acid residues around phosphorylated Ser1180.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.
靶标信息
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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