Invitrogen

Phospho-Acinus (Ser1180) Polyclonal Antibody

查看其他13个Acinus抗体

产品信息

PA5-64646

应用	建议稀释比	已发表文章
免疫印迹 (WB)	1:1,000	-

产品规格
种属反应	Human, Mouse, Rat
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	A synthesized peptide derived from human Acinus (Phospho-Ser1180) 查看免疫原
偶联物	Unconjugated
形式	Liquid
浓度	1 mg/mL
纯化类型	Affinity chromatography
保存液	PBS, pH 7.4, with 50% glycerol
内含物	0.02% sodium azide
保存条件	-20°C
RRID	AB_2665123

产品详细信息

Phospho-Acinus (Ser1180) Polyclonal Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.

靶标信息

ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152

基因别名: 2610036I19Rik; 2610510L13Rik; ACIN1; ACINUS; acinusL; acinusS; ACN; C79325; fSAP152; KIAA0670; mKIAA0670

UniProt ID: (Human) Q9UKV3, (Mouse) Q9JIX8

Entrez Gene ID: (Human) 22985, (Mouse) 56215, (Rat) 305884

分子生物学功能: protein modifying enzyme

positive regulation of defense response to virus by host mRNA processing cellular component disassembly involved in execution phase of apoptosis RNA splicing erythrocyte differentiation apoptotic chromosome condensation positive regulation of monocyte differentiation mitophagy in response to mitochondrial depolarization xenophagy apoptotic process regulation of autophagy regulation of apoptotic process positive regulation of apoptotic process negative regulation of mRNA splicing, via spliceosome

参与通路

nucleotide binding nucleic acid binding protein binding ATPase activity enzyme binding poly(A) RNA binding