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Invitrogen
Phospho-BCAR1 (Tyr165) Polyclonal Antibody
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Phospho-BCAR1 (Tyr165) Antibody (PA5-110108) in WB
Western blot analysis of Phospho-BCAR1 (Tyr165) in extracts of PC-12 cells. Samples were incubated with Phospho-BCAR1 (Tyr165) Polyclonal antibody (Product # PA5-110108) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. PC-12 cell lysate were treated by CIP (20 µL CIP for each 400 µL cell lysate) at 37°C for 1 hour. Lysates/proteins: 25 µg ... View More
产品信息
PA5-110108
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic phosphorylated peptide around Y165 of human BCAR1 (NP_0553822)
偶联物
形式
Liquid
浓度
0.26 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DLYQV
靶标信息
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCA1; breast cancer anti-estrogen resistance 1; Breast cancer anti-estrogen resistance protein 1; Cas scaffolding protein family member 1; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; p130cas; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate
基因别名: AI385681; BCAR1; CAS; CAS1; CASS1; CRKAS; P130CAS
UniProt ID: (Human) P56945, (Mouse) Q61140, (Rat) Q63767
Entrez Gene ID: (Human) 9564, (Mouse) 12927, (Rat) 25414
actin filament organization
cell adhesion
epidermal growth factor receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
insulin receptor signaling pathway
positive regulation of endothelial cell migration
cell migration
actin cytoskeleton organization
positive regulation of cell migration
cellular response to hepatocyte growth factor stimulus
platelet-derived growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
hepatocyte growth factor receptor signaling pathway
antigen receptor-mediated signaling pathway
B cell receptor signaling pathway
cell chemotaxis
signal transduction
regulation of cell growth
cell proliferation
regulation of apoptotic process
T cell receptor signaling pathway
cell division
