应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:1,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:50-1:100 | - |
免疫细胞化学 (ICC/IF) |
1:100-1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide sequence around phosphorylation site of tyrosine 24 (G-A-Y(p)-G-K) derived from Human CDK6. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2554127 |
A suggested positive control for Western blot is 293 cells; suggested positive control for IHC is human colon carcinoma; suggested positive control for ICC/IF is Hela cells.
Cyclin-dependent kinase 6 (p40cdk6 also known as PLSTIRE) belongs to a family of proteins designated as cdks. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell division protein kinase 6; CR2 protein kinase; CRK2; Cyclin-dependent kinase 6; MGC59692; Serine/threonine-protein kinase PLSTIRE
基因别名: 5830411I20; AI504062; CDK6; CDKN6; Crk2; MCPH12; PLSTIRE
UniProt ID: (Human) Q00534, (Mouse) Q64261
Entrez Gene ID: (Human) 1021, (Mouse) 12571