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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
免疫沉淀 (IP) |
1:25 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Non-human primate |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic phosphopeptide corresponding to residues surrounding pSer7 of human CENP-A protein |
偶联物 |
Unconjugated |
形式 |
Liquid |
纯化类型 |
Antigen affinity chromatography |
保存液 |
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
内含物 |
no preservative |
保存条件 |
-20°C |
RRID |
AB_10987142 |
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other histone proteins, including Histone H3.
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CENP A; CENP-A; Centromere autoantigen A; Centromere protein A; centromere protein A, 17kDa; centromere-specific histone; Histone H3-like centromeric protein A
基因别名: CenH3; CENP-A; CENPA
UniProt ID: (Human) P49450
Entrez Gene ID: (Human) 1058
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein
histone
