A suggested positive control for Western blot is HT29 cells; suggested positive control for IHC is human brain tissue.
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
蛋白别名: casein kinase 1, alpha 1; Casein kinase I isoform alpha; CK I alpha; CK-I alpha; CK1; CKI alpha; CKI-alpha; clock regulator kinase; CSNK1A1/CK1; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; YIL035C
基因别名: CK1; CK1a; CKIa; CSNK1A1; HEL-S-77p; HLCDGP1; PRO2975
UniProt ID: (Human) P48729
Entrez Gene ID: (Human) 1452