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Invitrogen
Phospho-Calmodulin 1/2/3 (Thr79, Ser81) Polyclonal Antibody
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Phospho-Calmodulin 1/2/3 (Thr79, Ser81) Antibody (PA5-118563) in ICC/IF
Immunocytochemical analysis of Phospho-Calmodulin 1/2/3 (Thr79, Ser81) in HepG2 cells using a Phospho-Calmodulin 1/2/3 (Thr79, Ser81) polyclonal antibody (Product # PA5-118563). The samples were with PFA and permeabilized in 0.1% saponin prior to blocking in 10% serum for 45 minutes at 37°C. The primary antibody was diluted 1:400 and incubated with the sample for 1 hour at 37°C. A Alexa Fluor 594 conjugated... View More
产品信息
PA5-118563
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human Calmodulin around the phosphorylation site of Thr79 and Ser81.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
靶标信息
Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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