Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-DNM1L (Ser637) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
PA5-117217
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic phosphorylated peptide around S637 of human DRP1 (NP_0361922)
偶联物
形式
Liquid
浓度
0.61 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: PC-12
Immunogen sequence: KLSARE
靶标信息
A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: C-terminal region; Dynamin-1-like protein; Dynamin-like protein; dynamin-like protein 1; dynamin-related protein 1; DYNIV 11; DYNIV-11; EC 3.6.5.5; FLJ41912; N-terminal region; VPS1
基因别名: DLP1; Dnm1l; Dnml1; Drp1
UniProt ID: (Rat) O35303
Entrez Gene ID: (Rat) 114114
mitochondrial fission
release of cytochrome c from mitochondria
dynamin polymerization involved in mitochondrial fission
endocytosis
metabolic process
regulation of mitochondrion organization
peroxisome fission
regulation of protein oligomerization
positive regulation of apoptotic process
mitochondrial fragmentation involved in apoptotic process
positive regulation of protein secretion
protein homotetramerization
membrane fusion
necroptotic process
mitochondrion morphogenesis
protein localization to mitochondrion
positive regulation of mitochondrial fission
mitochondrial membrane fission
positive regulation of release of cytochrome c from mitochondria
regulation of peroxisome organization
regulation of mitophagy
positive regulation of intrinsic apoptotic signaling pathway
