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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2554172 |
A suggested positive control for Western blot is JK cells.
EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AF-1p protein; ALL1 fused gene from chromosome 1; epidermal growth factor pathway substrate 15; Epidermal growth factor receptor substrate 15; Protein AF-1p; Protein Eps15
基因别名: 2410112D09Rik; AF-1P; AF1P; EPS15; MLLT5; RGD1307641
UniProt ID: (Human) P42566, (Mouse) P42567
Entrez Gene ID: (Human) 2060, (Mouse) 13858, (Rat) 313474
分子生物学功能:
membrane traffic protein
