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产品信息
PA5-64721
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human Tel (Phospho-Ser257) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2662850 |
产品详细信息
Phospho-ETV6 (Ser257) Polyclonal Antibody detects endogenous levels of ETV6 only when phosphorylated at Ser257.
靶标信息
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and Maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CGI-108; CSL4; Csl4p; ETS translocation variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; hCsl4p; p13; RP11-452K12.9; SKI4; Ski4p; Tel; TEL1 oncogene; Transcription factor ETV6
基因别名: ETV6; TEL; TEL/ABL; TEL1; THC5
UniProt ID: (Human) P41212
Entrez Gene ID: (Human) 2120
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
