应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:1,000 | - |
免疫细胞化学 (ICC/IF) |
1:100-1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide sequence around phosphorylation site of tyrosine 588/596 (K-T-Y(p)-V-R)/(R-T-Y(p)-V-D) derived from Human EPHA2/3/4. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2554419 |
A suggested positive control for Western blot is HepG2 cells; suggested positive control for ICC/IF is Hela cells.
The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12),EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, Ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EK4; EK8; EPH-like kinase 4; EPH-like kinase 8; Eph-like tyrosine kinase 1; Ephrin A2; Ephrin A3; Ephrin A4; Ephrin type-A receptor 2; Ephrin type-A receptor 3; Ephrin type-A receptor 4; EphrinA2; EphrinA3; EphrinA4; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; HEK; Human embryo kinase; human embryo kinase 1; receptor protein-tyrosine kinase HEK8; soluble EPHA2 variant 1; testicular tissue protein Li 64; TYRO1 protein tyrosine kinase; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor ETK1; Tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor MPK-5; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase receptor SEK-2; Tyrosine-protein kinase TYRO1; Tyrosine-protein kinase TYRO4
基因别名: 2900005C20Rik; AI385584; ARCC2; AW492086; AW545284; Cek4; Cek8; CTPA; CTPP1; CTRCT6; ECK; EK4; End3; EPHA2; EPHA3; EPHA4; ETK; ETK1; HEK; HEK4; HEK8; Mek4; Myk2; rb; SEK; Sek-2; Sek1; Sek2; TYRO1; TYRO4
UniProt ID: (Human) P29317, (Human) P29320, (Human) P54764, (Mouse) Q03145, (Mouse) Q80VZ2
Entrez Gene ID: (Human) 1969, (Human) 2042, (Human) 2043, (Mouse) 13836, (Mouse) 13837, (Mouse) 13838
分子生物学功能:
transmembrane signal receptor