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Invitrogen
Phospho-IGF1R beta (Tyr1158, Tyr1162, Tyr1163) Polyclonal Antibody
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产品信息
PA1-26725
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide corresponding to a portion of IR/IGF1R containing tyrosines 1158, 1162, and 1163 of human insulin receptor.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-26725 detects Insulin Receptor / IGF1R (phospho Y1158 + Y1162 + Y1163) from human and mouse samples. PA1-26725 is expected to cross react with rat (100% conserved) due to sequence homology.
PA1-26725 has been successfully used in Western blot procedures.
The PA1-26725 immunogen is a synthetic phosphopeptide corresponding to a portion of IR/IGF1R containing tyrosines 1158, 1162, and 1163 of human insulin receptor (tyrosines 1131, 1135 and 1136 in IGF1R).
靶标信息
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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