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Invitrogen
Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody
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Phospho-JNK1/JNK2 (Thr183, Tyr185) Antibody (PA1-28425) in WB
Western blot analysis of Phospho-JNK1 + JNK2 pThr183 + pTyr185 in 293, untreated or treated with UV, and PC12 cells untreated or treated with sorbitol. Samples were probed with a Phospho-JNK1 + JNK2 pThr183 + pTyr185 polyclonal antibody (Product # PA1-28425).
产品信息
PA1-28425
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide (Human) derived from the region of JNK 1 + 2 that contains threonine 183 and tyrosine 185, based on the human sequence.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-28425 detects JNK1 + JNK2 phospho T183, Y185 from human samples. PA1-28425 is expected to react with a wide range of other species due to sequence homology.
PA1-28425 has been successfully used in Western blot applications.
The PA1-28425 immunogen is a synthetic peptide (Human) derived from the region of JNK 1 + 2 that contains threonine 183 and tyrosine 185, based on the human sequence. This region is conserved among many species including human, rat, mouse, chick, nematode
靶标信息
C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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