Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.1-1 µg/mL | 查看7篇已发表文章 7篇已发表文章 |
免疫组化 (IHC) |
- | 查看2篇已发表文章 2篇已发表文章 |
免疫组化(石蜡) (IHC (P)) |
1:10-1:100 | - |
免疫细胞化学 (ICC/IF) |
4-6 µg/mL | - |
流式细胞分析 (Flow) |
0.5-5 µg/1x10^6 cells | - |
酶联免疫吸附实验 (ELISA) |
1-5 µg/mL | - |
染色质免疫沉淀 实验 (ChIP) |
1 µL | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
已发表种属 |
Human, Insect, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Recombinant Monoclonal |
类型 |
Antibody |
克隆号 |
D12H7L17 |
抗原 |
A peptide corresponding to amino acids 179-189 and 180-189 of P45983 and P45984, respectively. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS |
内含物 |
0.09% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2532273 |
This antibody is predicted to react with mouse, rat, primate, canine, bovine, porcine, chicken, equine, zebrafish and Xenopus based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; JNK 55; JNK-46; JNK-55; JNK/SAPK alpha; JNK1 beta1 protein kinase; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; Mitogen-activated protein kinase 9; OTTHUMP00000019552; Phospho-JNK; PRKM; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK 1; SAPK1a; SAPK1c; stress-activated protein kinase 1; Stress-activated protein kinase 1a; Stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2
基因别名: AI849689; AI851083; JNK; JNK-46; JNK-55; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK8; MAPK9; p54a; p54aSAPK; PRKM8; PRKM9; SAPK; SAPK1; SAPK1A; SAPK1C
UniProt ID: (Human) Q15713, (Human) P45984, (Mouse) Q91Y86, (Mouse) Q9WTU6
Entrez Gene ID: (Human) 5599, (Human) 5601, (Mouse) 26419, (Mouse) 26420