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Antibody detects endogenous levels of Kv3.4/KCNC4 only when phosphorylated at Ser15.
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: K+ channel subunit; KSHIIIC; MGC126818; potassium channel, voltage gated Shaw related subfamily C, member 4; potassium voltage gated channel, Shaw-related subfamily, member 4; Potassium voltage-gated channel subfamily C member 4; potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (Raw3); potassium voltage-gated channel, Shaw-related subfamily, member 4; Raw3; Voltage-gated potassium channel KCNC4; Voltage-gated potassium channel subunit Kv3.4
基因别名: AI850292; C1orf30; HKSHIIIC; KCNC4; Kcr2-4; KSHIIIC; KV3.4
UniProt ID: (Human) Q03721, (Mouse) Q8R1C0, (Rat) Q63734
Entrez Gene ID: (Human) 3749, (Mouse) 99738, (Rat) 684516