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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:1,000 | - |
免疫细胞化学 (ICC/IF) |
1:100-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide sequence around phosphorylation site of serine 162 (K-K-S(p)-F-K) derived from Human MARCKS. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2554240 |
A suggested positive control for Western blot is 293 cells; suggested positive control for ICC/IF is Hela cells.
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 80K protein; 80K-L protein; FLJ14368; FLJ90045; MARCKS; MARCS; Myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; protein kinase C substrate 80 kDa protein; Protein kinase C substrate, 80 kDa protein, light chain
基因别名: 80K-L; KINC; MACS; MARCKS; PKCSL; PRKCSL
UniProt ID: (Human) P29966, (Mouse) P26645
Entrez Gene ID: (Human) 4082, (Rat) 25603, (Mouse) 17118
