A suggested positive control for IHC is human breast carcinoma.
The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
蛋白别名: MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
基因别名: A430079H05Rik; ADCAD1; MEF2; MEF2A; RSRFC4; RSRFC9
分子生物学功能: MADS box transcription factor