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产品信息
PA5-64596
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human MSK2 (Phospho-Ser196) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2662227 |
产品详细信息
Phospho-MSK2 (Ser196) Polyclonal Antibody detects endogenous levels of MSK2 only when phosphorylated at Ser196.
靶标信息
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 90 kDa ribosomal protein S6 kinase 4; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase-2; Nuclear mitogen- and stress-activated protein kinase 2; Ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; RLSK; RSK-like protein kinase; S6K-alpha-4
基因别名: 1110069D02Rik; 90kDa; AI848992; mMSK2; Msk2; Rps6ka4
UniProt ID: (Mouse) Q9Z2B9
Entrez Gene ID: (Mouse) 56613
分子生物学功能:
protein modifying enzyme
regulation of transcription, DNA-templated
protein phosphorylation
inflammatory response
phosphorylation
positive regulation of histone phosphorylation
positive regulation of histone acetylation
intracellular signal transduction
histone H3-S10 phosphorylation
histone H3-S28 phosphorylation
positive regulation of transcription from RNA polymerase II promoter
interleukin-1-mediated signaling pathway
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
histone kinase activity (H3-S10 specific)
mitogen-activated protein kinase p38 binding
