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Invitrogen
Phospho-MYL2 (Ser19) Recombinant Rabbit Monoclonal Antibody (RM484)
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Phospho-MYL2 (Ser19) Antibody (MA562160) in WB
Western Blot analysis of mouse heart tissue lysate using Phospho-MYL2 (Ser19) recombinant monoclonal antibody (Product # MA562160) at 1:1,000 dilution. The phospho-specificity of RM484 was verified by peptide blocking using a control non-phosphopeptide or phosphopeptide targeting residue Ser19.
产品信息
MA562160
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM484
抗原
A phospho-peptide corresponding to human Phospho-Myl2 (Ser19).
偶联物
形式
Liquid
浓度
Conc. Not Determined
纯化类型
Protein A
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
This antibody reacts to Myl2 (Myosin Light Chain 2v) only when phosphorylated at Ser19. There is no cross-reactivity to Myl2 that is not phosphorylated. This antibody reacts to human, mouse or rat Phospho-Myl2 (Ser19).
靶标信息
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cardiac myosin light chain 2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC-2; MLC-2s/v; MLC-2v; Myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain phosphatase; myosin light chain-2; Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; Ventricular myosin light chain 2
基因别名: CMH10; MLC-2s/v; MLC2; MYL2
UniProt ID: (Human) P10916
Entrez Gene ID: (Human) 4633
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
post-embryonic development
muscle filament sliding
negative regulation of cell growth
muscle cell fate specification
muscle fiber development
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
