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产品信息
PA5-64837
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human NDEL1 (Phospho-Thr219) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2664701 |
产品详细信息
Phospho-NDEL1 (Thr219) Polyclonal Antibody detects endogenous levels of NDEL1 only when phosphorylated at Thr219.
靶标信息
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp451M0318; endooligopeptidase A; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel
基因别名: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDE2; NUDEL
UniProt ID: (Human) Q9GZM8, (Rat) Q78PB6, (Mouse) Q9ERR1
Entrez Gene ID: (Human) 81565, (Rat) 170845, (Mouse) 83431
establishment of mitotic spindle orientation
microtubule cytoskeleton organization
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
neuron projection development
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
canonical Wnt signaling pathway
neuron projection extension
sister chromatid cohesion
regulation of intracellular protein transport
positive regulation of GTPase activity
activation of GTPase activity
regulation of microtubule motor activity
transport
multicellular organism development
nervous system development
cell differentiation
