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A suggested positive control for Western blot is HepG2 cells.
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
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蛋白别名: Choline phosphatase 1; hPLD1; phophatidylcholine-specific; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
基因别名: PLD1
UniProt ID: (Human) Q13393
Entrez Gene ID: (Human) 5337
分子生物学功能:
phospholipase
