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Invitrogen
Phospho-Paxillin (Tyr118) Polyclonal Antibody
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产品信息
PA5-17828
产品规格
已发表种属
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide corresponding to residues surrounding pTyr118 of human paxillin
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other tyrosine phosphorylated proteins.
靶标信息
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
